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Anti-Sperm Antibodies and Infertility

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Created December 19, 2025

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We can now move to the discussion of “Category 4 of Repro-immunologic Disorder- the Antibodies

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to Sperm or Anti-sperm antibodies. Some women produce antibodies that attack sperm,

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an autoimmune response to sperm antigens. These antibodies can prevent sperm from moving or fertilizing

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the egg. As a result, conception becomes difficult or impossible. Early testing can

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identify this condition, and specialized treatments can help improve fertility. If you struggle

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with infertility, consult your Reproductive Immunologist.”

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