How THC Affects the Brain and Body

When you smoke weed, THC rapidly enters the bloodstream and reaches the brain.

There, it binds to cannabinoid receptors in the endocannabinoid system — a network

that shapes mood, memory, and perception. This interaction triggers dopamine

release, creating the euphoric "high." THC also alters the hippocampus,

affecting short-term memory, and changes activity in the cerebellum and basal ganglia,

reducing coordination and slowing reaction time. At the same time, heart rate increases

and blood vessels dilate, causing red eyes. In the lungs, smoke can irritate

tissue, leading to coughing and short-term respiratory discomfort.