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Mechanoneural Interfaces for Bionic Limbs

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Created November 11, 2025

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Mechanoneural interfaces for bionic integration Growing knowledge in peripheral nerve regeneration and

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soft tissue reconstruction has enabled a novel development of tissue constructs combined with artificial

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interfacing technologies with the purpose of giving sensation to limb prostheses. Afferent and efferent

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signalling pathways are used in such a way that mechanoneural interfaces have demonstrated a capability

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to enhance prosthetic control and convey somatosensory sensation. First and foremost, what is a mechanoneural

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interface? It combines surgically modified assemblies of soft tissues containing nerves

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and muscles with artificial components to enhance neural signalling for reconstruction of bionic limbs.

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