The Mirtazapine Paradox Explained

Unlock the secret every psych doc knows: the Mirtazapine paradox. Low doses knock

you out, high doses perk you up. Here’s why: at 15mg, H1 histamine blockade

reigns, bringing on that deep, foggy sleep and munchie cravings.

But ramp up to 30mg or 45mg, and watch as noradrenaline and serotonin release kicks in,

energizing your mood like never before. Choose wisely: low for sleep and appetite,

high for energy and motivation. It’s a counterintuitive twist—but once you get it,

it clicks into place perfectly.