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Understanding Diabetes Mellitus and Its Types

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Created November 11, 2025

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Diabetes mellitus is a chronic condition caused by relative or absolute insulin deficiency.

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This insulin deficiency results in hyperglycaemia, which in the long term can affect many organs,

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in particular the blood vessels, nerves, eyes and kidneys (see Overview of

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complications of diabetes). Diabetes can be classified as: type 1 diabetes—a

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condition of insulin deficiency most commonly caused by immune-mediated destruction of the

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insulin-producing pancreatic beta cells; see type 1 diabetes in children and adolescents

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and type 1 diabetes in adults type 2 diabetes—a condition of relative insulin deficiency

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caused by progressive loss of pancreatic beta-cell insulin secretion on a background of insulin resistance;

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