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Understanding Trypsin-Like Immunoreactivity (TLI) in Dogs

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Created October 7, 2025

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Trypsin-like immunoreactivity, or TLI, is a vital diagnostic test. It measures pancreatic

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enzymes like trypsinogen in the bloodstream. High levels suggest pancreatitis; low levels indicate insufficiency.

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In dogs, TLI is key for diagnosing Exocrine Pancreatic Insufficiency. EPI means the

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pancreas doesn't produce enough digestive enzymes. Dogs with EPI often suffer from chronic weight loss

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and diarrhea. The TLI test is highly specific for confirming this condition.

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Early diagnosis allows effective treatment, greatly improving their health.

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