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The Exposome Outweighs Genetics in Longevity

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Created December 26, 2025

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Your environment is ten times more important than your DNA for predicting how long you live.

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Scientists have officially moved beyond just looking at genetics to something called the exposome.

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This tracks absolutely every chemical, stressor, and pollutant you’ve absorbed over your

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entire lifetime. Using new mass spectrometry tech on blood samples and silicone wristbands, researchers can

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now see invisible chemical footprints left by everything from your gas stove to your daily coffee.

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They found that these environmental factors interact with your biology to drive disease

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far more than genetic risk alone. This is the new era of precision medicine.

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Read the full paper in PNAS.

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