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The Rise of High Fructose Corn Syrup

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Created December 11, 2025

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Video Transcript

Full text from the video

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When chemists Richard Marshall and Earl Kooi started fiddling with cornstarch, the powder made

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from the dense insides of corn kernels, their intention was to turn glucose, which is easily

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produced from the starch, into fructose, which is sweeter. The idea wasn’t

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that far-fetched. The two sugar molecules are cousins, both made from the same atomic parts

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slightly rearranged. The duo’s experiment, which took place at the Corn Products Refining Company

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in Argo, Ill., was a success. Marshall and Kooi discovered that

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the bacterium Aeromonas hydrophila produced an enzyme that could reconfigure the components of glucose

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from corn like so many Lego blocks. It was the first leap forward for a food industry

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