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Understanding Lipedema: A Connective Tissue Disorder

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Created December 17, 2025

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Lipedema is actually a connective tissue disorder, not a fat problem. Your body is essentially

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overproducing collagen, turning the flexible netting around your fat cells into a rigid brick wall.

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This fibrosis suffocates the tissue and crushes your nerves and blood vessels, which causes that

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specific, intense pain and swelling. It is driven by estrogen,

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which explains why it almost exclusively affects women. Standard calorie cutting usually

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fails here, but new research shows a low-carb diet reduced pain four times more

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than a low-fat diet. You don't just need to lose weight, you need to lower inflammation to

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break down those collagen walls.

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